Sumoylation 10x Reaction Buffer

(Catalog # B010)

Description:

Each tube contains 200 µl of sumoylation 10x reaction buffer (200 mM Hepes pH 7.5, 50mM MgCl2, 20mM ATP).

Assay Conditions:

Sumoylation assays are carried out in a final volume of 20µl in reaction condition (20 mM Hepes pH 7.5, 5mM MgCl2, 2mM ATP). We would recommend to add fresh 2mM ATP to be sure that sufficient energy is supplied.

Sumoylation Protocol:

1.      Prepare the suitable purified substrate protein.

2.      In each reaction, add 1 µl UBC9 (E2) to substrate first, then 1 µl Sumo-1, 2 µl 10x reaction buffer, 1 µl Aos1/Uba2 (E1). Finally, add H2O to bring up to 20 µl (we would recommend to add fresh 2mM ATP to be sure that sufficient energy is supplied).

3.      The best reaction concentration of  proteins is as following:

E I:                  7.5µg/ml

E II:                 50µg/ml

SUMO-1:       50µg/ml

Legal consideration: FOR RESEARCH USE ONLY. 

Price

Cat#

Item Spec Price (USD) Stock location

Polyclonal Antibodies

AP018

Sumo I (full length)

100µl

300

FOB Taiwan

AP021

SUMO-1 (11-101)

100µl

300

FOB Taiwan

AP025

NEDD8

100µl

300

FOB Taiwan

Proteins

P006

Aos1/Uba2 (Good for 100 reactions)

4.5µg

150

FOB Taiwan

P018

Aos1/Uba2 (Good for 100 reactions)

15µg

400

FOB Taiwan

P019

UBC9 (Good for 100 reactions)

100µg

100

FOB Taiwan

P020

SUMO-1 (Good for 100 reactions)

100µg

100

FOB Taiwan

Kits

K011

SUMO Proteins

Convenient Pack

300

FOB Taiwan

K010

SUMO control Kit

30 reactions

500

FOB Taiwan